Lucidenic acid benefit and side effects, found in reishi muhroom

Ganoderma lucidum is known as a medicinal mushroom that contains lucidenic acid.

Lucidenic acid B induces apoptosis in human leukemia cells via a mitochondria-mediated pathway.
J Agric Food Chem. 2008 Jun 11; Department of Food Science and Biotechnology, National Chung Hsing University, 250 Kuokuang Road, Taichung 40227, Taiwan.
Ganoderma lucidum is known as a medicinal mushroom used in traditional Chinese medicine. In the present study, the effect of lucidenic acids (A, B, C, and N) isolated from a new G. lucidum (YK-02) on induction of cell apoptosis and the apoptotic pathway in HL-60 cells were investigated. The results demonstrated that lucidenic acids decreased cell population growth of HL-60 cells. Our finding may be critical to the chemopreventive potential of lucidenic acid B.

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